Saturday, January 2, 2010

Jaundice


a condition characterized by the unusual presence of bile pigment circulating in the blood. Jaundice is caused by the bile produced in the liver, which should go into the intestines, passing instead into the circulation because of some obstruction. The symptoms of jaundice include a yellowing of the skin and the whites of the eyes.

Taken from Dictionary of Science

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Jaundice, also known as icterus (attributive adjective: icteric), is a yellowish discoloration of the skin, the conjunctival membranes over the sclerae (whites of the eyes), and other mucous membranes caused by hyperbilirubinemia (increased levels of bilirubin in the blood). This hyperbilirubinemia subsequently causes increased levels of bilirubin in the extracellular fluids. Typically, the concentration of bilirubin in the plasma must exceed 1.5 mg/dL, three times the usual value of approximately 0.5 mg/dL, for the coloration to be easily visible. Jaundice comes from the French word jaune, meaning yellow.


One of the first tissues to change color as bilirubin levels rise in jaundice is the conjunctiva of the eye, a condition sometimes referred to as scleral icterus. However, the sclera themselves are not "icteric" (stained with bile pigment) but rather the conjunctival membranes that overlie them. The yellowing of the "white of the eye" is thus more properly conjunctival icterus.


Taken from Wikipedia

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